(IN BRIEF) Researchers have identified a previously unknown mechanism that helps melanoma cells spread and resist immunotherapy. The study, published in The EMBO Journal, shows that the protein NGFR activates a pathway involving MLC2, increasing tumour invasiveness while contributing to … Read the full press release →
Posted in Education, Healthcare, Non Profit, Pharma & Biotech, Science, Spain, United Kingdom
Tagged advanced melanoma, Barts Charity, biomarker, Blocking NGFR May Help Restore Immunotherapy Sensitivity in Melanoma Models, Breast Cancer Now, cancer biology, Cancer Research UK, cancer spread, cancer treatment, CNB-CSIC, combination treatment, experimental drug, Héctor Peinado, ICR, ICR Scientists Help Identify Potential New Target for Resistant Advanced Melanoma, immune checkpoint therapy, immunotherapy resistance, Madrid, melanoma, metastasis, MLC2, myosin II signalling pathway, myosin light chain 2, nerve growth factor receptor, New Research Uncovers Hidden Mechanism Behind Melanoma Spread and Treatment Resistance, NGFR, oncology, preclinical research, skin cancer, Spain, The EMBO Journal, The Institute of Cancer Research, THX-B, tumour invasion, UK Research and Innovation, United Kingdom, University of London, Victoria Sanz-Moreno, Worldwide Cancer Research
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