(IN BRIEF) A new study led through collaboration between The Institute of Cancer Research, the Karolinska Institute, and Uppsala University has found that some cases of iAMP21, a rare high-risk subtype of paediatric acute lymphoblastic leukaemia, may begin before birth. … Read the full press release
Posted in Healthcare, News, Pharma & Biotech, Science, Technology, United Kingdom
Tagged all®, bone marrow, cancer evolution, Center for Medical Mass Screening in Sweden, childhood cancer research, childhood leukaemia, chromosome 21 amplification, clonal evolution, Dr Gustaf Leijonhufvud, Dr Tony Ford, Dr Viktor Ljungström, Early Detection, genetic alterations, genetic rearrangement, Haematologica, heel prick tests, high-risk leukaemia, iAMP21, ICR, intrachromosomal amplification of chromosome 21, Karolinska Institute, Karolinska University Hospital, London, lymphocytes, May 26 2026, neonatal blood spots, New ICR-Led Research Traces Early Genetic Origins of High-Risk Childhood Leukaemia to Neonatal Blood Samples, New Study Shows Neonatal Blood Spots Can Reveal Early Genetic Alterations Associated with iAMP21 Leukaemia, paediatric acute lymphoblastic leukaemia, paediatric cancer, pre-ALL clone, pre-leukaemic changes, prenatal origins, Professor Britt Gustafsson, Professor Sir Mel Greaves, Researchers Uncover Evidence That Rare Childhood Leukaemia Subtype Can Begin Years Before Diagnosis, Sweden, Swedish Childhood Cancer Society, The Institute of Cancer Research, The Institute of Cancer Research Study Finds Rare Childhood Leukaemia Subtype Can Begin Before Birth, The Institute of Cancer Research Study Finds Rare Childhood Leukaemia Subtype May Originate Before Birth, United Kingdom, Uppsala University
(IN BRIEF) Researchers at The Institute of Cancer Research have published new findings showing that delayed exposure to common microbes may trigger childhood acute lymphoblastic leukaemia (ALL) in genetically susceptible individuals, while early-life microbial exposure may help protect against the … Read the full press release
Posted in Business, Education, Financial, Healthcare, Industrial, Investment, Management, Marketing, Science, Technology, United Kingdom
Tagged acute lymphoblastic leukaemia, all®, B-cell development, B-cell precursor ALL, cancer biology, cancer prevention research, Cancer Research UK, childhood cancer prevention, childhood cancer research, childhood immunity, childhood leukaemia, delayed infection hypothesis, Elham Shamsaei, epidemiological studies, ETV6::RUNX1, Experimental Study Supports Long-Standing Theory Connecting Delayed Infections and Childhood ALL, genetic mutations, gut microbiome, Haematologica, ICR, immune system development, immune training, infection timing, inflammatory response, leukaemia risk, microbial exposure, microbiome, paediatric oncology, probiotics, Professor Sir Mel Greaves, Scientists Identify Critical Early-Life Immune Window in Childhood Leukaemia Research, The Institute of Cancer Research
(IN BRIEF) Scientists at The Institute of Cancer Research in London have uncovered new details about how the CDK11 enzyme is activated and regulated, providing insights that could support future cancer drug development. Using cryo-electron microscopy, the team mapped the … Read the full press release
Posted in Education, Healthcare, Pharma & Biotech, Science, Technology, United Kingdom
Tagged Amy McGeoch, Breakthrough Research Maps Active CDK11 Complex and Its Role in Gene Expression and RNA Splicing, cancer cell growth, cancer research, Cancer Therapies, CDK11, cell division, cellular biology, cryo-electron microscopy, Cryo-EM, cyclin L, cyclin-dependent kinase, Dr Basil Greber, drug development, enzyme regulation, gene expression, gene transcription, ICR, London, Medical Research Council, Molecular Biology, Nature Communications, New Findings from London Researchers Advance Understanding of Cellular Enzyme Involved in Cancer Growth, oncology research, protein complex, pseudo-substrate, RNA splicing, SAP30BP, Scientists Uncover Structural Secrets of CDK11 That Could Support Future Cancer Drug Development, spliceosome, structural biology, The Institute of Cancer Research, therapeutic research
(IN BRIEF) Researchers from The Institute of Cancer Research and Queen’s University Belfast have developed an AI tool to improve the accuracy and consistency of PD-L1 scoring in lung cancer diagnosis. The system uses deep learning to assist pathologists in … Read the full press release
Posted in Artificial Intelligence (AI), Education, Healthcare, Pharma & Biotech, Science, Technology, United Kingdom
Tagged artificial intelligence, biomarker analysis, digital pathology, immunotherapy, lung cancer, Manuel Salto-Tellez, non-small cell lung carcinoma, NSCLC, oncology, PD-L1, precision medicine, Queen's University Belfast, Researchers advance digital pathology with new AI solution for more reliable lung cancer diagnostics, Scientific Reports, The Institute of Cancer Research, TPS, Tumour Proportion Score
(IN BRIEF) Researchers at The Institute of Cancer Research, London, have achieved a breakthrough in the treatment of advanced sarcoma and melanoma through a novel combination of isolated limb perfusion (ILP) and oncolytic virus therapy. In the first clinical trial … Read the full press release
Posted in Healthcare, News, Pharma & Biotech, Science, Technology, United Kingdom
Tagged Amgen Pharmaceuticals, cancer research, clinical trial, Dr Lucy Bull Foundation, ICR, ILP, immunotherapy, isolated limb perfusion, Journal for ImmunoTherapy of Cancer, London, Mabs Mardulyn Charitable Foundation, melanoma, NIHR Biomedical Research Centre, oncolytic virus, Professor Alan Melcher, Professor Andrew Hayes, Robert McAlpine Foundation, Royal Marsden Melanoma and Sarcoma Research Fund, sarcoma, Sarcoma UK, T-VEC, talimogene laherparepvec, The Institute of Cancer Research, The Institute of Cancer Research pioneers new dual treatment combining virus therapy and isolated limb perfusion to enhance immune response in advanced cancer, The Royal Marsden NHS Foundation Trust, tumour immunity, United Kingdom, virotherapy
(IN BRIEF) The Institute of Cancer Research, London, has published two major studies demonstrating how pairing a cancer-killing reovirus with targeted therapies such as talazoparib and palbociclib can greatly strengthen immune activity and tumour destruction. By disrupting cancer cell defences … Read the full press release
Posted in Business, Education, Financial, Healthcare, Industrial, Investment, Management, Marketing, News, Science, Technology, United Kingdom
Tagged Cancer Research UK, immune activation, immune checkpoint inhibitors, Joan Kyula-Currie, Kevin Harrington, London, Nature Communications, oncolytic virus, Oncolytics Biotech, Palbociclib, PARP-1, personalised cancer therapies, reovirus, RIG-I, Royal Marsden, talazoparib, The Institute of Cancer Research, tumour stress response, Victoria Roulstone, virotherapy
(IN BRIEF) The largest study to date on testicular germ cell tumours (TGCTs) has revealed a potential link between testicular cancer risk and rare genetic variants affecting cellular movement and structure. Conducted by The Institute of Cancer Research, London, the … Read the full press release
Posted in Business, Financial, Healthcare, Industrial, Investment, Management, News, Science, Technology, United Kingdom
Tagged cancer genetics, cell movement genes, Clare Turnbull, DNA mutations, European Urology Open Science, genetic risk, heritability in cancer, Movember Foundation, personalised medicine, rare genetic variants, testicular cancer, testicular germ cell tumours, TGCT, The Institute of Cancer Research, translational genomics, UK Biobank, whole-exome sequencing, Zeid Kuzbari
(IN BRIEF) A groundbreaking AI-powered research platform, POETIC-AI, has been unveiled by scientists from The Institute of Cancer Research, promising to accelerate cancer biomarker discovery. Demonstrated at The Alan Turing Institute’s fifth AI UK conference, the platform integrates diverse clinical … Read the full press release
Posted in Artificial Intelligence (AI), Business, Education, Financial, Healthcare, Industrial, Investment, Management, News, Science, Technology, United Kingdom
Tagged artificial intelligence, biomarkers, cancer research, Cancer Research UK, clinical trial data, Collaborative Research, CT, digital pathology, Dr. Ferran Cardo, Dr. Maggie Cheang, hormone therapy, ICR, Integrated Discovery and Diagnostics programme, Ki67, medical imaging, MRI, natural language AI, Palantir Foundry, POETIC trial, POETIC-AI, Professor Manuel Salto-Tellez, Royal Marsden NHS Foundation Trust, The Institute of Cancer Research, Xixuan Zhu
(IN BRIEF) Scientists at The Institute of Cancer Research in London have made significant strides in understanding why some cases of neuroblastoma—a pediatric cancer of nerve tissue—result in poorer outcomes. Their research indicates that mutations in the ATRX gene, which … Read the full press release
Posted in Healthcare, News, Pharma & Biotech, Science, Technology, United Kingdom
Tagged ATRX gene, Cancer Letters, Cancer Research UK, Dr Sally George, Federica Lorenzi, high-risk, immune cell infiltration, inflammatory pathways, macrophages, MYCN gene amplification, Neuroblastoma, Neuroblastoma UK, paediatric oncology, personalised therapy, targeted treatment, The Institute of Cancer Research, TIME, tumour immune microenvironment
LONDON, 16-Nov-2017 — /EuropaWire/ — The Institute of Cancer Research, London, welcomes the approval by NICE of a new type of treatment for women with previously untreated advanced breast cancer. Palbociclib and ribociclib, two new drugs approved today for use on the NHS, … Read the full press release
Scientists have identified weak spots in cancer cells that could be targeted and attacked by new precision drugs. BRIGHTON, 2-3-2015 — /EuropaWire/ — A major computational analysis by scientists at the University of Sussex and The Institute of Cancer Research, … Read the full press release
Posted in Education, Healthcare, Science, United Kingdom
Tagged Cancer Research UK, Daphne Jackson Trust, Dr Bissan Al-Lazikani, Dr Frances Pearl, drugs that exploit the inherent weaknesses of cancer cells, Nature Reviews Cancer, Professor Laurence Pearl, Professor Paul Workman, The Institute of Cancer Research, The Institute of Cancer Research scientists, Tony Carr, University of Sussex
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