(IN BRIEF) Scientists at The Institute of Cancer Research in London have uncovered new details about how the CDK11 enzyme is activated and regulated, providing insights that could support future cancer drug development. Using cryo-electron microscopy, the team mapped the … Read the full press release
Posted in Education, Healthcare, Pharma & Biotech, Science, Technology, United Kingdom
Tagged Amy McGeoch, Breakthrough Research Maps Active CDK11 Complex and Its Role in Gene Expression and RNA Splicing, cancer cell growth, cancer research, Cancer Therapies, CDK11, cell division, cellular biology, cryo-electron microscopy, Cryo-EM, cyclin L, cyclin-dependent kinase, Dr Basil Greber, drug development, enzyme regulation, gene expression, gene transcription, ICR, London, Medical Research Council, Molecular Biology, Nature Communications, New Findings from London Researchers Advance Understanding of Cellular Enzyme Involved in Cancer Growth, oncology research, protein complex, pseudo-substrate, RNA splicing, SAP30BP, Scientists Uncover Structural Secrets of CDK11 That Could Support Future Cancer Drug Development, spliceosome, structural biology, The Institute of Cancer Research, therapeutic research
(IN BRIEF) Loughborough University and the University of Oxford have collaborated on a groundbreaking study that has resulted in the development of a small molecule probe. This probe specifically binds to inositol pyrophosphate (5-PP-InsP5), a crucial cellular messenger involved in … Read the full press release
Posted in Education, Healthcare, Pharma & Biotech, Science, Technology, United Kingdom
Tagged 5-PP-InsP5, biological processes, cell growth, cellular messenger, Dr Felix Plasser, Dr Stephen Butler, enzyme regulation, Fathima Jamion, inositol pyrophosphate, Loughborough University, Megan Shipton, Pick of the Week, Professor Barry Potter, programmed cell death, regulator of blood glucose levels, small molecule probe, therapeutic drugs, University of Oxford
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