(IN BRIEF) Novartis has reported final Phase III ALIGN study results showing that Vanrafia (atrasentan) slowed kidney function decline in adults with IgA nephropathy compared with placebo. At Week 136, the therapy demonstrated a 2.39 ml/min/1.73m² difference in eGFR change … Read the full press release →
Posted in Business, Healthcare, Pharma & Biotech, Switzerland
Tagged accelerated approval United States China, ALIGN study, atrasentan, EGFR, endothelin A receptor antagonist, Fabhalta, Final ALIGN Data Support Vanrafia as Potential Foundational Therapy to Slow Kidney Function Decline in IgAN, IgA nephropathy, IgAN, iptacopan, kidney disease, Novartis, Novartis Advances IgA Nephropathy Portfolio with Positive Long-Term Phase III Results for Vanrafia, phase III clinical trial, proteinuria, RAS inhibitors, renal function decline, Ruchira Glaser, SGLT2 inhibitors, Vanrafia, zigakibart
(IN BRIEF) Novartis has reported positive interim results from its Phase III ALIGN study involving atrasentan, an oral endothelin A receptor antagonist, for the treatment of IgA nephropathy (IgAN). The study demonstrated that atrasentan significantly reduced proteinuria (excess protein in … Read the full press release →
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