The Institute of Cancer Research

(IN BRIEF) Researchers from The Institute of Cancer Research and Queen’s University Belfast have developed an AI tool to improve the accuracy and consistency of PD-L1 scoring in lung cancer diagnosis. The system uses deep learning to assist pathologists in … Read the full press release →

(IN BRIEF) Researchers from The Institute of Cancer Research and The University of Manchester have created the most comprehensive map of cancer-related genetic mutations to date, analysing data from nearly 11,000 patients in the 100,000 Genomes Project. The study identified … Read the full press release →

(IN BRIEF) Scientists at the Institute of Cancer Research in London are contributing to an international clinical trial evaluating THEO-260, an experimental oncolytic immunotherapy designed to treat platinum-resistant ovarian cancer. The trial, known as OCTOPOD-IV, is being supported by €8 … Read the full press release →

(IN BRIEF) Researchers at The Institute of Cancer Research, London have created a next-generation PROTAC degrader that successfully eliminates the cancer-related protein Aurora A while overcoming the hook effect that has limited earlier degraders. The new molecule, CCT400028, demonstrates improved … Read the full press release →

(IN BRIEF) Researchers at The Institute of Cancer Research, London, have found that the precise location of ATRX gene mutations plays a critical role in determining how neuroblastoma tumours behave and respond to treatment. Published in Neoplasia and supported by … Read the full press release →

(IN BRIEF) The Institute of Cancer Research, London has appointed Dr Michelle Harrison to its Board of Trustees, bringing extensive experience in global public policy, corporate leadership, and charity governance to the organisation’s governing body. A former Chief Executive and … Read the full press release →

(IN BRIEF) Researchers at The Institute of Cancer Research, London, have uncovered how the DNA repair enzyme XPF-ERCC1 is recruited to sites of damage and activated inside cells, resolving a long-standing question in molecular biology and providing structural insights that … Read the full press release →

(IN BRIEF) The Institute of Cancer Research has welcomed Sutton Council’s approval of ambitious plans led by Aviva Capital Partners and Socius to create around one million square feet of new life-sciences research and laboratory space across a 12-acre site … Read the full press release →

(IN BRIEF) The Institute of Cancer Research, London, has led the development of OPTIMISE-ROR, the first structured guidance outlining how patient-reported outcomes should be used in early-stage cancer dose-finding trials. Published in the Journal of Clinical Oncology, the recommendations provide … Read the full press release →

(IN BRIEF) The Institute of Cancer Research has welcomed NICE’s recommendation of talazoparib in combination with enzalutamide for adults with metastatic prostate cancer, providing a new treatment option for around 2,400 patients in England who are unsuitable for chemotherapy. Backed … Read the full press release →

(IN BRIEF) Researchers at the Institute of Cancer Research and St Mark’s Hospital are launching a major study analysing historic bowel cancer samples dating back more than 70 years to understand why diagnoses are rising in people under 50. By … Read the full press release →