(IN BRIEF) Roche and Nurix Therapeutics have entered into an exclusive global licensing and collaboration agreement to co-develop and co-commercialise bexobrutideg, also known as NX-5948, an investigational oral BTK degrader with potential applications across malignant haematology, immunology and neurology. The … Read the full press release
Posted in Business, European Union, Financial, Government, Healthcare, Industrial, Investment, Law, Management, Marketing, Pharma & Biotech, Science, Switzerland, Technology
Tagged Arthur T Sands, B-cell malignancies, bexobrutideg, brain-penetrant therapy, Bruton’s tyrosine kinase, BTK, BTK degrader, BTK inhibitors, chronic lymphocytic leukaemia, chronic spontaneous urticaria, CLL, co-commercialisation, co-development, CSU, Hart-Scott-Rodino Antitrust Improvements Act, immunology, Immunology and Neurology Pipeline with Global Bexobrutideg Collaboration, kinase activity, Levi Garraway, licensing agreement, malignant haematology, MS, multiple sclerosis, Neurology, NHL, Non-Hodgkin lymphoma, Nurix Therapeutics, NX-5948, oncology pipeline, oral therapy, Phase 3 clinical trial, relapsed or refractory B-cell malignancies, Roche, Roche and Nurix Announce Up to USD 2.3 Billion Collaboration to Develop and Commercialise Bexobrutideg, Roche and Nurix Therapeutics Partner on Potential Best-in-Class Targeted Protein Degrader for B-Cell Malignancies, Roche oncology, Roche Strengthens Oncology, scaffolding function, Switzerland, targeted protein degradation, targeted protein degrader, treatment resistance, United States, USD 2.3 billion deal value, USD 700 million upfront payment
The trial, called CALAVI, will assess the effect of Calquence on the exaggerated immune response of patients hospitalised with COVID-19 infection (PRESS RELEASE) CAMBRIDGE, 14-Apr-2020 — /EuropaWire/ — Pharmaceutical giant AstraZeneca to begin a randomised, global clinical trial to assess … Read the full press release
Posted in Healthcare, Science, Sweden, Technology, United Kingdom
Tagged assisted ventilation, AstraZeneca, best supportive care, blood cancers, Bruton’s tyrosine kinase, BSC, BTK, BTK inhibitor, CALAVI, Calquence, clinical trial, COVID-19, cytokine storm, exaggerated immune response, inflammatory cytokines, José Baselga, Louis M. Staudt M.D. Ph.D., lung disease
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