Tag Archives: PIK3CA mutation

Novartis Advances Precision Medicine Strategy with Agreement to Acquire SNV4818 for HR Positive HER2 Negative Breast Cancer

(IN BRIEF) Novartis has agreed to acquire SNV4818 from Synnovation Therapeutics, a next-generation PI3Kα inhibitor designed to selectively target mutations in HR+/HER2- breast cancer. The therapy, currently in Phase 1/2 clinical trials, aims to improve treatment tolerability by focusing on … Read the full press release

Roche’s Itovebi Regimen Shows Significant Survival Benefits for HR-Positive Breast Cancer in Phase III Trial Results

(IN BRIEF) Roche announced the publication of pivotal phase III results for its Itovebi™ (inavolisib)-based regimen at the Clinical Trials in Alzheimer’s Disease congress, demonstrating a 57% reduction in the risk of disease progression or death in patients with HR-positive, … Read the full press release