(IN BRIEF) Researchers at The Institute of Cancer Research, London, have achieved a breakthrough in the treatment of advanced sarcoma and melanoma through a novel combination of isolated limb perfusion (ILP) and oncolytic virus therapy. In the first clinical trial … Read the full press release
Posted in Healthcare, News, Pharma & Biotech, Science, Technology, United Kingdom
Tagged Amgen Pharmaceuticals, cancer research, clinical trial, Dr Lucy Bull Foundation, ICR, ILP, immunotherapy, isolated limb perfusion, Journal for ImmunoTherapy of Cancer, London, Mabs Mardulyn Charitable Foundation, melanoma, NIHR Biomedical Research Centre, oncolytic virus, Professor Alan Melcher, Professor Andrew Hayes, Robert McAlpine Foundation, Royal Marsden Melanoma and Sarcoma Research Fund, sarcoma, Sarcoma UK, T-VEC, talimogene laherparepvec, The Institute of Cancer Research, The Institute of Cancer Research pioneers new dual treatment combining virus therapy and isolated limb perfusion to enhance immune response in advanced cancer, The Royal Marsden NHS Foundation Trust, tumour immunity, United Kingdom, virotherapy
(IN BRIEF) The Phase III RAMPART trial has demonstrated that combining the immunotherapy drugs durvalumab and tremelimumab after surgery significantly improves disease-free survival in patients with early-stage renal cell carcinoma (RCC). Led by the Medical Research Council Clinical Trials Unit … Read the full press release
Posted in Education, Healthcare, News, Pharma & Biotech, Science, Technology, United Kingdom
Tagged AstraZeneca UK Limited, cancer recurrence, clinical trial, Combination Therapy, disease-free survival, durvalumab, ESMO 2025, European Society for Medical Oncology, ICR, immunotherapy, kidney cancer, Medical Research Council Clinical Trials Unit, MRC CTU, oncology research, precision medicine, Professor Angela Meade, Professor James Larkin, RAMPART trial, RAMPART trial confirms combination immunotherapy reduces recurrence risk in kidney cancer after surgery, RCC, renal cell carcinoma, The Institute of Cancer Research and Royal Marsden report breakthrough results in renal cancer immunotherapy trial, The Institute of Cancer Research London, The Royal Marsden Cancer Charity, The Royal Marsden NHS Foundation Trust, tremelimumab, UCL, University College London
(IN BRIEF) Long-term data from the international monarchE trial has confirmed that patients with HR+ and HER2- node-positive high-risk early breast cancer achieve better survival outcomes when treated with the targeted therapy abemaciclib in combination with standard hormone therapy. Presented … Read the full press release
Posted in Education, Healthcare, News, Pharma & Biotech, Science, Technology, United Kingdom
Tagged abemaciclib, Annals of Oncology, clinical trial, early breast cancer, Eli Lilly and Company, ESMO 2025, European Society for Medical Oncology, HER2 negative, high-risk breast cancer, hormone therapy, HR-positive, ICR, Long-term monarchE study confirms abemaciclib improves survival for high-risk early breast cancer patients, Long-Term Survival, metastatic disease, monarchE trial, National Institute for Health and Care Research, New monarchE data shows first major advance in adjuvant breast cancer survival outcomes in two decades, NIHR, oncology research, Professor Stephen Johnston, targeted therapy, The Institute of Cancer Research London, The Royal Marsden Cancer Charity, The Royal Marsden NHS Foundation Trust
(IN BRIEF) In recognition of World Statistics Day 2025, The Institute of Cancer Research (ICR), London, is spotlighting the essential role of statisticians in advancing cancer research through reliable, transparent, and responsible data analysis. The event, themed “Quality statistics and … Read the full press release
Posted in Education, Healthcare, News, Pharma & Biotech, Science, Technology, United Kingdom
Tagged adaptive trial designs, artificial intelligence, biostatistics, cancer trials, clinical research, Clinical Trials and Statistics Unit, Covid-19 pandemic, CTSU, data transparency, Emily Alger, evidence-based decision making, ICR, ICR showcases how statistical science powers cancer research and clinical progress for World Statistics Day 2025, Machine Learning, oncology research, patient-reported outcomes, Professor Christina Yap, quality statistics, responsible research, statistical science, The Institute of Cancer Research celebrates the power of statistics in advancing cancer research ahead of World Statistics Day 2025, The Institute of Cancer Research London, University of Oxford, University of Warwick, World Statistics Day 2025
(IN BRIEF) A new global analysis by The Institute of Cancer Research (ICR), London, has found that cancer incidence is rising in both younger and older adults, disputing the idea that the global increase is limited to those under 50. … Read the full press release
Posted in Education, Healthcare, News, Pharma & Biotech, Science, Technology, United Kingdom
Tagged Annals of Internal Medicine, bowel cancer, breast cancer, cancer incidence, Cancer Prevention, early-onset cancer, endometrial cancer, epidemiology, Global analysis from ICR challenges belief that cancer surge affects only younger adults, Global study, global trends, GLOBOCAN, IARC, ICR, International Agency for Research on Cancer, kidney cancer, leukaemia, Obesity, Older Adults, Professor Amy Berrington, Professor Kristian Helin, public health, screening, The Institute of Cancer Research London, The Institute of Cancer Research study finds cancer rates rising among both younger and older adults worldwide, thyroid cancer, World Health Organization, younger adults
(IN BRIEF) A new study led by researchers at The Institute of Cancer Research, London, has identified a promising new combination therapy for pancreatic cancer that could transform future treatment. The dual approach — combining boiling histotripsy and oncolytic reovirus … Read the full press release
Posted in Business, Education, Healthcare, News, Pharma & Biotech, Science, Technology, United Kingdom
Tagged boiling histotripsy, cancer research, cancer treatment innovation, Gail ter Haar, ICR, ICR study identifies new immune-based combination strategy to improve pancreatic cancer treatment outcomes, immune response, immunotherapy, Institute of Cancer Research, macrophages, neutrophils, oncolytic reovirus, pancreatic cancer, Pancreatic cancer study from ICR highlights new dual treatment approach and reveals key immune cell insights, Pancreatic Cancer UK, Petros Mouratidis, Pharmaceutics, preclinical study, The Institute of Cancer Research identifies promising dual treatment strategy for pancreatic cancer, tumour microenvironment, ultrasound therapy, viral immunotherapy
(IN BRIEF) The Institute of Cancer Research has renewed its Athena Swan Silver Award for 2025–2029, recognising continued progress in promoting gender equality and fostering an inclusive workplace. The award highlights key achievements such as improved recruitment and flexible working … Read the full press release
Posted in Business, Education, Healthcare, Management, News, Pharma & Biotech, Science, Society, Technology, United Kingdom
Tagged academic leadership, Advance HE, Alan Cumber, and research culture, Athena Swan action plan, Athena Swan Silver Award, career development, diversity, Diversity And Inclusion, Dr Barbara Pittam, equity in research, flexible working, gender equality, Gender Pay Gap, higher education, ICR, ICR recognised for advancing inclusive excellence with Athena Swan Silver Award renewal through 2029, ICR secures four-year Athena Swan Silver Award recognising progress in equity, Institute of Cancer Research, Institute of Cancer Research celebrates renewed Athena Swan Silver Award with new gender equality action plan, Pathway to Independence program, Professor Christina Yap, Professor Kristian Helin, research culture, Technician Career Pathways
(IN BRIEF) The Institute of Cancer Research and NEOsphere Biotechnologies have announced a new collaboration to accelerate the discovery of molecular glue degrader drugs, an innovative approach in targeted cancer therapy. The partnership will integrate ICR’s proprietary molecular glue library … Read the full press release
Posted in Business, Education, Healthcare, News, Pharma & Biotech, Science, Technology, United Kingdom
Tagged Academic–industry partnership to accelerate rational design of molecular glue degrader drugs for cancer treatment, artificial intelligence, Cancer Drug Discovery, cancer research innovation, Centre for Protein Degradation, computational drug design, E3 ligases, Henrik Daub, high-throughput proteomics, ICR, ICR and NEOsphere Biotechnologies join forces to pioneer systematic discovery of molecular glue degrader therapies, Institute of Cancer Research, Institute of Cancer Research and NEOsphere Biotechnologies partner to advance molecular glue degrader drug discovery, Jonathan Beech, Machine Learning, MGDs, molecular glue degraders, molecular glue library, Monte Rosa Therapeutics, Nature Communications, NEOsphere Biotechnologies, Novartis, proteomics, St Jude Children’s Research Hospital, targeted protein degradation, Zoran Rankovic
(IN BRIEF) A landmark international study has provided robust evidence that elevated levels of prolactin, a hormone involved in breast development, increase the risk of breast cancer in post-menopausal women. Researchers from The Institute of Cancer Research in London, along … Read the full press release
Posted in Business, Education, Financial, Healthcare, Industrial, Investment, Management, News, Science, Technology, United Kingdom
Tagged B2Risk consortium, BMI, breast cancer, Breast Cancer Now, cohort studies, Dr Simon Vincent, early diagnosis, ICR, Institute of Cancer Research, invasive breast cancer, mammographic density, personalized prevention, plasma levels, PMH, polygenic risk score, post-menopausal, Professor Montse Garcia-Closas, prolactin, risk factor, targeted interventions
(IN BRIEF) A groundbreaking AI-powered research platform, POETIC-AI, has been unveiled by scientists from The Institute of Cancer Research, promising to accelerate cancer biomarker discovery. Demonstrated at The Alan Turing Institute’s fifth AI UK conference, the platform integrates diverse clinical … Read the full press release
Posted in Artificial Intelligence (AI), Business, Education, Financial, Healthcare, Industrial, Investment, Management, News, Science, Technology, United Kingdom
Tagged artificial intelligence, biomarkers, cancer research, Cancer Research UK, clinical trial data, Collaborative Research, CT, digital pathology, Dr. Ferran Cardo, Dr. Maggie Cheang, hormone therapy, ICR, Integrated Discovery and Diagnostics programme, Ki67, medical imaging, MRI, natural language AI, Palantir Foundry, POETIC trial, POETIC-AI, Professor Manuel Salto-Tellez, Royal Marsden NHS Foundation Trust, The Institute of Cancer Research, Xixuan Zhu
(IN BRIEF) Researchers have made a significant breakthrough in cancer drug discovery by identifying a new binding site on the eukaryotic initiation factor 4E (eIF4E), a protein long considered undruggable. The collaborative study between The Institute of Cancer Research (ICR) … Read the full press release
Posted in Healthcare, Pharma & Biotech, Science, Technology, United Kingdom
Tagged anticancer therapies, Astex Pharmaceuticals, breast cancer, Cancer Drug Discovery, Cancer Research UK, cancer treatment, Centre for Cancer Drug Discovery, drug development, druggable binding sites, eIF4E, eIF4G, fragment-based screening, ICR, Institute of Cancer Research, Nature Communications, new drug targets, Olivia Rossanese, Paul Clarke, prostate cancer, protein degradation, protein synthesis, protein synthesis regulation, small molecule inhibitors, therapeutic innovation, undruggable protein
(IN BRIEF) Researchers from The Institute of Cancer Research, London, and Barts Cancer Institute have discovered how the extracellular matrix (ECM) surrounding tumours influences cancer cells to become aggressive and spread throughout the body. Their study, published in Nature Communications, … Read the full press release
Posted in Business, Education, Financial, Healthcare, Industrial, Investment, Management, News, Science, Technology, United Kingdom
Tagged Barts Cancer Institute, breast cancer, cancer metastasis, cancer research, Cancer Therapies, cancer treatment, early cancer detection, ECM, extracellular matrix, ICR, lysyl oxidase, melanoma, metastasis, metastasis prevention, Nature Communications, tumor behavior, tumor biology
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