Tag Archives: B cell depletion

Novartis Phase III Trials Show Ianalumab Significantly Improves Outcomes in Sjögren’s Disease

(IN BRIEF) Novartis has reported landmark Phase III results showing that ianalumab significantly reduced disease activity in patients with Sjögren’s disease, meeting primary endpoints in both the NEPTUNUS-1 and NEPTUNUS-2 trials. The treatment, which combines B-cell depletion and BAFF-R inhibition, … Read the full press release

Sanofi Completes $600 Million Acquisition of DR-0201 to Enhance Immunology Pipeline and Advance Autoimmune Disease Treatments

(IN BRIEF) Sanofi has completed the acquisition of DR-0201 from Dren Bio, now renamed SAR448501, to enhance its immunology pipeline. This bispecific myeloid cell engager, which has shown promising results in B-cell depletion, may offer potential breakthroughs in autoimmune diseases, … Read the full press release

Boehringer Ingelheim and Cue Biopharma Forge Strategic Partnership to Advance Targeted Autoimmune Therapy

(IN BRIEF) Boehringer Ingelheim has entered into a multi-year collaboration with Cue Biopharma to develop and commercialize CUE-501, a first-in-class bispecific compound designed to selectively deplete harmful B cells in autoimmune diseases. The innovative therapy uses Cue’s Immuno-STAT™ platform to … Read the full press release