(IN BRIEF) Researchers at The Institute of Cancer Research, London have created a next-generation PROTAC degrader that successfully eliminates the cancer-related protein Aurora A while overcoming the hook effect that has limited earlier degraders. The new molecule, CCT400028, demonstrates improved … Read the full press release
Posted in Business, Education, Financial, Healthcare, Industrial, Investment, Management, Pharma & Biotech, Science, Technology, United Kingdom
Tagged alisertib, Aurora A kinase, Cancer Research UK, cancer therapeutics, CCT400028, chemical probes, Children’s Brain Tumour Centre of Excellence CBTCE, Gary Newton, glioma, hook effect, Institute of Cancer Research Develops Advanced Aurora A PROTAC Degrader That Overcomes Hook Effect and Improves Stability, Institute of Cancer Research London, Journal of Medicinal Chemistry, leukaemia, Lindsay Evans, Neuroblastoma, New Aurora A Degrader from Institute of Cancer Research Demonstrates Improved Selectivity and Reliability in Cancer Studies, paediatric cancers, Paul Workman, PROTAC, protein degradation technology, targeted protein degradation, University of Kiel
(PRESS RELEASE) VENLO, the Netherlands, 8-Jan-2021 — /EuropaWire/ — QIAGEN announces the appointment of Dr. Toralf Haag as a member of the Supervisory Board with immediate effect. He will also become a member of the Audit Committee. Dr. Haag was … Read the full press release
Posted in Management, Netherlands, News, Pharma & Biotech, Science, Technology
Tagged appointment, Assay technologies, Audit Committee, Bioinformatics, biomolecules, diagnostics, DNA, Dr. Toralf Haag, Lawrence Rosen, life sciences, Lonza Group AG, Molecular Diagnostics, QIAGEN, RNA, Sample to Insight, Supervisory Board, Thyssen Handelsunion AG, University of Augsburg, University of Kiel, Voith GmbH & Co. KGaA
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