14-3-2013 — /europawire.eu/ — Die Humboldt-Universität zu Berlin (HU) hat am Nachmittag des 7. März 2013 in Kooperation mit der Charité – Universitätsmedizin Berlin und dem Max-Delbrück-Centrum für Molekulare Medizin (MDC) in einem Festakt das neue Integrative Forschungsinstitut (IRI) für Lebenswissenschaften gegründet. Ziel des IRI ist es, den Campus Nord der HU zu einem maßgebenden Wissenschaftspark im Herzen Berlins weiterzuentwickeln, um die gemeinsame Grundlagenforschung in den Bereichen Systembiologie und Theoretische Biologie, den Neurowissenschaften sowie der Infektionsbiologie und Immunologie voranzutreiben. Wissenschaftlerinnen und Wissenschaftler dieser Disziplinen forschen im IRI Hand in Hand und decken das Wissen um das Leben von der molekularen bis zur komplexen organismischen Ebene ab, um den Fokus für Prävention, Diagnostik und Therapie im klinischen Alltag zu stärken.
„In engem Schulterschluss mit unseren Kooperationspartnern wollen wir diesen einzigartigen Campus in der Mitte Berlins zu einem international sichtbaren Ort der lebenswissenschaftlichen Spitzenforschung machen. Die überregionale Bedeutung der Berliner Lebenswissenschaften zeigt sich aktuell auch an der Entwicklung des vom Bund geförderten Berliner Instituts für Gesundheitsforschung (BIG) des MDC und der Charité, in das die Berliner Universitäten ihre lebenswissenschaftliche Forschung gerne stärker einbringen möchten. Das IRI für Lebenswissenschaften setzt durch seine wissenschaftliche Ausrichtung einen komplementären Schwerpunkt zu den patientenorientierten Forschungsthemen des BIG“, sagt HU-Präsident Prof. Dr. Jan-Hendrik Olbertz.
Der Campus Nord der HU hat sich in den vergangenen Jahren zu einem lebendigen Ort der Spitzenforschung in der Biologie, der Medizin und den Neurowissenschaften entwickelt. Wissenschaftlerinnen und Wissenschaftler des Instituts für Biologie der HU, der Charité – Universitätsmedizin Berlin, des Bernstein Zentrums für Computational Neuroscience (BCCN) Berlin, des Max-Planck-Instituts für Infektionsbiologie und des Deutschen Rheuma-Forschungszentrums Berlin arbeiten hier bereits eng zusammen. Diese erfolgreiche Konstellation wird bis 2018 durch die Ansiedlung des Berlin Institute for Medical Systems Biology (BIMSB) des MDC sowie einen Forschungsneubau für die HU-Biologie ergänzt.
“Die Humboldt-Universität schafft im IRI für Lebenswissenschaften mit der Charité und dem MDC als außeruniversitärer Einrichtung der Helmholtz-Gemeinschaft einen Rahmen für exzellente Forschung, die im internationalen Wettbewerb an der Spitze mitspielt. Das MDC wird vor Ort mit dem BIMBS vertreten sein. Im BIMSB kooperieren MDC-Wissenschaftler schon seit langem erfolgreich mit der Humboldt-Universität. Das ist der Weg, der in die Zukunft führt. Wir sind zuversichtlich, dass heute der Grundstein für die Förderung der Spitzenforschung auf diesem lebenswissenschaftlichen Campus gelegt wird. Sie wird im Rahmen künftiger Initiativen des Bundes und der Länder umfassend Entfaltung finden“, sagt Prof. Dr. Walter Rosenthal, Vorstandsvorsitzender und wissenschaftlicher Stiftungsvorstand des MDC.
Ausgehend von aktuellen Schwerpunkten der biomedizinischen Forschung wird das IRI für Lebenswissenschaften gleichermaßen die Verbindung zwischen experimentellen und theoretischen Methoden sowie klinischen Anwendungsgebieten stärken. Dies betrifft die Übergänge zu Erkrankungen des Nervensystems mit dem Exzellenzcluster NeuroCure und dem Centrum für Schlaganfallforschung Berlin, der Krebsforschung mit der Graduiertenschule Berlin School of Integrative Oncology sowie der regenerativen Medizin, vertreten durch das Berlin-Brandenburger Centrum für Regenerative Therapien und die Berlin-Brandenburger Schule für Regenerative Therapien.
Die kooperative Nutzung wegweisender Technologie- und Infrastrukturen, eine frühe Nachwuchsförderung und Gemeinschaftsprofessuren setzen dabei in den gemeinsamen Forschungsprojekten Synergien frei, die ihren Niederschlag beispielsweise auf den Gebieten der Regenerativen Therapien und der Krebstherapie finden. „Die Gründung des IRI für Lebenswissenschaften ist somit auch ein wichtiger Meilenstein in der Entwicklung Berlins zu einem zentralen, international sichtbaren Standort der lebenswissenschaftlichen Forschung in Deutschland“, erklärt Prof. Dr. Annette Grüters-Kieslich, Dekanin der Charité – Universitätsmedizin Berlin.
Aktuelle Forschungsprojekte
Aktuell forschen die Kooperationspartner im IRI Lebenswissenschaften beispielsweise im vom BMBF geförderten Verbundprojekt „ViroSign – Systemvirologie von Influenza – Molekulare Signatur der permissiven Virusinfektion“ nach Faktoren, die über eine erfolgreiche Influenzainfektion bestimmen. Ziel ist es, die charakteristischen Proteinsignaturen (Proteom) einer Wirtszelle und das möglichst vollständige Netzwerk aller Virus-Wirtszell-Interaktionen nach einer Infektion durch Influenzaviren in seiner zeitlichen Dynamik zu charakterisieren. Das interdisziplinäre Netzwerk ermöglicht es, einen großen Bogen der angewendeten Methoden und Techniken zu spannen, der von der globalen Analyse des zellulären Proteoms bis zu einer einzelnen infizierten Zelle reicht. „Das IRI ermöglicht es uns, effektiver über die Fächergrenzen hinweg zu forschen, um hier einen Grundstein für die gezielte Bekämpfung von Infektionen zu legen. Forschungsergebnisse können so zum Wohle der Patienten schneller angewandt werden“, erläutert Prof. Dr. Andreas Herrmann, Professor für Molekulare Biophysik an der Humboldt-Universität zu Berlin und Sprecher des IRI für Lebenswissenschaften.
So werden etwa im Projekt OncoPATH am Beispiel eines bösartigen Darmtumors die qualitativen und quantitativen Auswirkungen häufiger genetischer und epigenetischer Veränderungen auf die Signalwege und Netzwerke der Tumorzellen zu analysieren. Hierzu werden experimentelle Modelle erstellt, in denen die in Tumoren häufig vorkommenden genetischen Mutationen induziert werden können. Die Auswirkungen dieser Veränderungen auf die Signalwegaktivierung, einen regulierten Zelltod (Apoptoseinduktion), Zellwachstum und Therapieresistenz werden getestet, funktionell analysiert und in ein mathematisches Modell integriert. Das Modell kann dann eingesetzt werden, um therapeutische Interferenzen zu simulieren und neue, therapeutische Möglichkeiten vorherzusagen.
Das IRI für Lebenswissenschaften ist eines der drei Integrativen Forschungsinstitute der Humboldt Universität. Die Integrativen Forschungsinstitute sind fakultätsübergreifende Institute. Sie unterstützen forschungsstarke inneruniversitäre Kooperationen und tragen entscheidend zur Profilbildung der Universität bei. Darüber hinaus öffnen sie die Universitäten für die längst überfällige, auch strukturelle Vernetzung von universitärer und außeruniversitärer Forschung.
Pressematerial und weitere Informationen
Kontakt
Constanze Haase
Pressesprecherin
Humboldt-Universität zu Berlin
Tel.: 030 2093-2332
constanze.haase@hu-berlin.de
IRI für die Lebenswissenschaften
Prof. Dr. Andreas Herrmann (Sprecher)
Dipl.-Ing. Uta Kaufhold (Kommiss. Geschäftsführerin)
Tel.: 030 2093-8327
iri-lifesciences@hu-berlin.de
www.iri-lifesciences.de
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- Digi Communications NV announces Investors Call for the Q1 2021 Financial Results
- Digi Communications N.V. announces an Amendment to the 2021 Financial Calendar
- Fastpayhotels Hits an Industry Milestone by Connecting 500 Hotels Per Day Through DerbySoft Technology
- 4 ways to build a more flexible supply chain
- Join the world's leading virtual CBD event for FREE
- DEEPENING STRATEGIC RELATIONSHIP BETWEEN UBC AND PIONEERING DECENTRALISED PLATFORM, MANYONE
- Mono Solutions recognizes Norwegian small business agency with best website 2021 award
- Mono Solutions and Xrysos Odigos unlock new opportunities for small businesses
- Behind the scenes of a 10,000-people online conference: creating a live-event atmosphere and leveraging cybersecurity software
- Largest Supply Chain for Face masks, FFP2, FFP3 and cloth masks
- TRANSMAR AND TRANSMETRICS SIGN DEAL FOR STATE-OF-THE-ART LOGISTICS COLLABORATION
- Amendment of Digi Communications N.V. Financial Calendar for 2021
- 4iG and Digi Communications NV’s Romanian subsidiary have entered into a term sheet with regards to a potential acquisition by 4iG of DIGI Group’s Hungarian operations
- “Building Healthy Relationships and Enhancing Gender Equality”: Young women from Cyprus, Egypt, Lebanon and Jordan come together
- Bring Ventures investit dans Crossborderit (CBIT), DDP et une solution de commerce électronique
- Bring Ventures investiert in Crossborderit (CBIT), eine DDP (geliefert verzollt) und E-Commerce Lösung
- Bring Ventures invests in Crossborderit (CBIT), DDP and ecommerce solution
- Lionspeed GP with Patrick Kolb and Lorenzo Rocco joins forces with CarCollection Motorsport in 2021
- Eurekos, ein klassenbester LMS-Anbieter, hat seine Position im renommierten Fosway 9-Grid™ für Lernsysteme verbessert
- Eurekos, en førsteklasses LMS-udbyder, har forstærket sin position på den prestigefyldte Fosway 9-Grid™ for læringssystemer
- Eurekos, ein erstklassiger LMS-Anbieter, hat seine Position auf dem renommierten Fosway 9-Grid™ für Lernsysteme weiter ausgebaut
- Digi Communications N.V. announces Share transaction made by an executive director of the Company with class B shares
- Digi Communications N.V.: Announces an Amendment to the Financial Calendar for 2021
- Ideanomics Invests $13M in Italian EV Motorcycle Company, Energica
- DigiSky and Asman Technology Announce Global Reseller Agreement
- Neowintech - O Marketplace Da Sua Próxima Solução Financeira
- Neowintech - Il Marketplace per la tua prossima soluzione finanziaria
- PIONEERING DECENTRALISED SECURE MESSAGING PLATFORM MANYONE ANNOUNCES STRATEGIC RELATIONSHIP WITH UNIVERSITY COLLEGE LONDON CENTRE BLOCKCHAIN TECHNOLOGY
- Digi Communications NV announces the release of the 2020 Preliminary Financial Results
- Fraunhofer IGD develops automated robotic arm to scan cultural objects in 3D, now cooperating with Phase One
- Adapt Fast or Disappear – Choosing the Right Supplier
- Digi Communications NV announces Investors Call for the 2020 Preliminary Financial Results
- A URSAPHARM Arzneimittel e a CEBINA anunciam uma parceria com vista a reaproveitar o anti-histamínico azelastina para combater a COVID-19
- URSAPHARM Arzneimittel et CEBINA annoncent un partenariat pour reconvertir l'antihistaminique azélastine afin de lutter contre la COVID-19
- URSAPHARM Arzneimittel y CEBINA anuncian una colaboración para readaptar el antihistamínico azelastine para combatir la COVID-19
- URSAPHARM Arzneimittel and CEBINA announce partnership to repurpose the antihistamine azelastine to combat COVID-19
- ANIL UZUN Will Launch Bass Guitar Lessons Series on Youtube
- Henrik Stampe Appointed CEO for Mono Solutions
- Anna Mossberg leder Nordens största privata AI-lab i Sverige: "Utan AI riskerar svenska företag att förlora sin konkurrensfördel."
- What COVID-19 has taught us about manufacturing & the importance of a digital online marketplace
- Digi Communications N.V. announces: the Supreme Court of Hungary dismissed the Company’s appeal related to the 5G Tender procedure
- Customer Data Platform Industry to Reach $1.5 Billion in 2021: CDP Institute Report
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GreenMantra Technologies Announces Exclusive Distribution Relationship with HARKE GROUP